Evolutionary Coupling Analysis of Q8IUX7
Secondary structure from ECs
EC score distribution and threshold
Alignment robustness analysis
Top ECs
| Rank |
Residue 1 |
Amino acid 1 |
Residue 2 |
Amino acid 2 |
EC score |
| 1 |
1096 |
E |
1120 |
Q |
0.85 |
| 2 |
1089 |
V |
1113 |
L |
0.81 |
| 3 |
1084 |
E |
1108 |
E |
0.76 |
| 4 |
1094 |
G |
1118 |
E |
0.75 |
| 5 |
1094 |
G |
1102 |
G |
0.75 |
| 6 |
1086 |
Y |
1110 |
E |
0.73 |
| 7 |
1101 |
F |
1125 |
F |
0.72 |
| 8 |
1090 |
V |
1114 |
E |
0.72 |
| 9 |
1102 |
G |
1126 |
E |
0.71 |
| 10 |
1083 |
T |
1107 |
P |
0.69 |
| 11 |
1104 |
K |
1128 |
E |
0.69 |
| 12 |
1095 |
T |
1119 |
T |
0.69 |
| 13 |
1106 |
E |
1130 |
E |
0.67 |
| 14 |
1082 |
E |
1106 |
E |
0.67 |
| 15 |
1100 |
E |
1124 |
E |
0.67 |
| 16 |
1093 |
F |
1109 |
F |
0.66 |
| 17 |
1090 |
V |
1098 |
E |
0.65 |
| 18 |
1082 |
E |
1098 |
E |
0.65 |
| 19 |
1096 |
E |
1104 |
K |
0.63 |
| 20 |
1097 |
V |
1105 |
V |
0.63 |
| 21 |
1112 |
Q |
1120 |
Q |
0.63 |
| 22 |
1122 |
E |
1130 |
E |
0.62 |
| 23 |
1092 |
E |
1116 |
E |
0.62 |
| 24 |
1087 |
T |
1111 |
T |
0.61 |
| 25 |
1081 |
S |
1105 |
V |
0.61 |
| 26 |
1076 |
A |
1124 |
E |
0.61 |
| 27 |
1088 |
E |
1112 |
Q |
0.60 |
| 28 |
1098 |
E |
1122 |
E |
0.60 |
| 29 |
1091 |
T |
1103 |
T |
0.59 |
| 30 |
1084 |
E |
1116 |
E |
0.58 |
| 31 |
1089 |
V |
1105 |
V |
0.58 |
| 32 |
1098 |
E |
1110 |
E |
0.58 |
| 33 |
1085 |
T |
1109 |
F |
0.58 |
| 34 |
1118 |
E |
1126 |
E |
0.57 |
| 35 |
1092 |
E |
1108 |
E |
0.56 |
| 36 |
1091 |
T |
1107 |
P |
0.56 |
| 37 |
1112 |
Q |
1124 |
E |
0.56 |
| 38 |
1092 |
E |
1104 |
K |
0.56 |
| 39 |
1097 |
V |
1121 |
L |
0.56 |
| 40 |
1072 |
P |
1080 |
E |
0.56 |
| 41 |
1088 |
E |
1104 |
K |
0.56 |
| 42 |
1093 |
F |
1117 |
F |
0.55 |
| 43 |
1082 |
E |
1090 |
V |
0.55 |
| 44 |
1117 |
F |
1125 |
F |
0.55 |
| 45 |
1093 |
F |
1105 |
V |
0.55 |
| 46 |
1078 |
W |
1086 |
Y |
0.55 |
| 47 |
1080 |
E |
1104 |
K |
0.55 |
| 48 |
1106 |
E |
1118 |
E |
0.55 |
| 49 |
1085 |
T |
1117 |
F |
0.54 |
| 50 |
1088 |
E |
1096 |
E |
0.54 |
| 51 |
1120 |
Q |
1128 |
E |
0.54 |
| 52 |
1081 |
S |
1129 |
E |
0.54 |
| 53 |
1108 |
E |
1120 |
Q |
0.53 |
| 54 |
1108 |
E |
1116 |
E |
0.53 |
| 55 |
1086 |
Y |
1094 |
G |
0.53 |
| 56 |
1092 |
E |
1124 |
E |
0.53 |
| 57 |
1084 |
E |
1100 |
E |
0.53 |
| 58 |
1086 |
Y |
1102 |
G |
0.53 |
| 59 |
1078 |
W |
1102 |
G |
0.52 |
| 60 |
1105 |
V |
1129 |
E |
0.52 |
| 61 |
1109 |
F |
1125 |
F |
0.52 |
| 62 |
1107 |
P |
1115 |
P |
0.52 |
| 63 |
1127 |
E |
1135 |
E |
0.52 |
| 64 |
1106 |
E |
1114 |
E |
0.52 |
| 65 |
1118 |
E |
1130 |
E |
0.52 |
| 66 |
1091 |
T |
1115 |
P |
0.51 |
| 67 |
1101 |
F |
1113 |
L |
0.51 |
| 68 |
1099 |
P |
1123 |
P |
0.51 |
| 69 |
1092 |
E |
1100 |
E |
0.50 |
| 70 |
1093 |
F |
1101 |
F |
0.50 |
| 71 |
1081 |
S |
1093 |
F |
0.50 |
| 72 |
1112 |
Q |
1128 |
E |
0.50 |
| 73 |
1095 |
T |
1107 |
P |
0.50 |
| 74 |
1062 |
S |
1070 |
L |
0.50 |
| 75 |
1110 |
E |
1118 |
E |
0.50 |
| 76 |
1105 |
V |
1113 |
L |
0.50 |
| 77 |
1087 |
T |
1099 |
P |
0.50 |
| 78 |
1066 |
E |
1074 |
T |
0.50 |
| 79 |
1074 |
T |
1098 |
E |
0.50 |
| 80 |
1103 |
T |
1111 |
T |
0.50 |
| 81 |
1114 |
E |
1122 |
E |
0.49 |
| 82 |
1136 |
E |
1140 |
G |
0.49 |
| 83 |
1119 |
T |
1131 |
E |
0.49 |
| 84 |
1100 |
E |
1108 |
E |
0.49 |
| 85 |
1102 |
G |
1114 |
E |
0.49 |
| 86 |
1123 |
P |
1131 |
E |
0.49 |
| 87 |
1104 |
K |
1116 |
E |
0.49 |
| 88 |
1095 |
T |
1103 |
T |
0.49 |
| 89 |
1126 |
E |
1134 |
E |
0.48 |
| 90 |
1046 |
P |
1050 |
P |
0.48 |
| 91 |
1097 |
V |
1113 |
L |
0.48 |
| 92 |
1076 |
A |
1100 |
E |
0.48 |
| 93 |
1108 |
E |
1132 |
E |
0.48 |
| 94 |
1097 |
V |
1129 |
E |
0.48 |
| 95 |
1083 |
T |
1095 |
T |
0.47 |
| 96 |
1061 |
L |
1069 |
G |
0.47 |
| 97 |
1098 |
E |
1106 |
E |
0.47 |
| 98 |
1101 |
F |
1117 |
F |
0.47 |
| 99 |
1096 |
E |
1112 |
Q |
0.47 |
| 100 |
1094 |
G |
1110 |
E |
0.47 |
| 101 |
1110 |
E |
1126 |
E |
0.47 |
| 102 |
1050 |
P |
1058 |
A |
0.46 |
| 103 |
1078 |
W |
1090 |
V |
0.46 |
| 104 |
1080 |
E |
1088 |
E |
0.46 |
| 105 |
1088 |
E |
1120 |
Q |
0.46 |
| 106 |
1117 |
F |
1129 |
E |
0.46 |
| 107 |
1107 |
P |
1131 |
E |
0.46 |
| 108 |
1107 |
P |
1119 |
T |
0.46 |
| 109 |
1087 |
T |
1095 |
T |
0.46 |
| 110 |
1076 |
A |
1084 |
E |
0.45 |
| 111 |
1116 |
E |
1128 |
E |
0.45 |
| 112 |
1089 |
V |
1101 |
F |
0.45 |
| 113 |
1094 |
G |
1106 |
E |
0.45 |
| 114 |
1105 |
V |
1117 |
F |
0.45 |
| 115 |
1104 |
K |
1112 |
Q |
0.45 |
| 116 |
1083 |
T |
1091 |
T |
0.45 |
| 117 |
1109 |
F |
1133 |
K |
0.45 |
| 118 |
1069 |
G |
1117 |
F |
0.44 |
| 119 |
1085 |
T |
1097 |
V |
0.44 |
| 120 |
1068 |
W |
1076 |
A |
0.44 |
| 121 |
1077 |
G |
1101 |
F |
0.44 |
| 122 |
1082 |
E |
1130 |
E |
0.44 |
| 123 |
1079 |
E |
1095 |
T |
0.44 |
| 124 |
1101 |
F |
1109 |
F |
0.44 |
| 125 |
1075 |
T |
1099 |
P |
0.44 |
| 126 |
1118 |
E |
1134 |
E |
0.44 |
| 127 |
1079 |
E |
1087 |
T |
0.44 |
| 128 |
1072 |
P |
1096 |
E |
0.44 |
| 129 |
1129 |
E |
1137 |
I |
0.44 |
| 130 |
1068 |
W |
1092 |
E |
0.44 |
| 131 |
1090 |
V |
1102 |
G |
0.44 |
| 132 |
1134 |
E |
1138 |
A |
0.43 |
| 133 |
1099 |
P |
1111 |
T |
0.43 |
| 134 |
1078 |
W |
1126 |
E |
0.43 |
| 135 |
1104 |
K |
1120 |
Q |
0.43 |
| 136 |
1138 |
A |
1142 |
A |
0.43 |
| 137 |
1110 |
E |
1122 |
E |
0.43 |
| 138 |
1066 |
E |
1070 |
L |
0.42 |
| 139 |
1105 |
V |
1121 |
L |
0.42 |
| 140 |
1132 |
E |
1140 |
G |
0.42 |
| 141 |
1078 |
W |
1110 |
E |
0.42 |
| 142 |
1046 |
P |
1054 |
P |
0.42 |
| 143 |
1084 |
E |
1092 |
E |
0.42 |
| 144 |
1116 |
E |
1132 |
E |
0.42 |
| 145 |
1057 |
P |
1065 |
I |
0.42 |
| 146 |
1058 |
A |
1066 |
E |
0.42 |
| 147 |
1073 |
P |
1121 |
L |
0.41 |
| 148 |
1074 |
T |
1122 |
E |
0.41 |
| 149 |
1103 |
T |
1119 |
T |
0.41 |
| 150 |
1048 |
T |
1052 |
T |
0.41 |
| 151 |
1116 |
E |
1124 |
E |
0.41 |
| 152 |
1120 |
Q |
1132 |
E |
0.41 |
| 153 |
1109 |
F |
1117 |
F |
0.41 |
| 154 |
1080 |
E |
1092 |
E |
0.41 |
| 155 |
1124 |
E |
1136 |
E |
0.41 |
| 156 |
1089 |
V |
1121 |
L |
0.40 |
| 157 |
1077 |
G |
1089 |
V |
0.40 |
| 158 |
1079 |
E |
1103 |
T |
0.40 |
| 159 |
1103 |
T |
1127 |
E |
0.40 |
| 160 |
1085 |
T |
1101 |
F |
0.40 |
| 161 |
1064 |
T |
1072 |
P |
0.40 |
| 162 |
1085 |
T |
1133 |
K |
0.40 |
| 163 |
1056 |
A |
1064 |
T |
0.40 |
| 164 |
1060 |
T |
1068 |
W |
0.40 |
| 165 |
1045 |
G |
1051 |
P |
0.40 |
| 166 |
1089 |
V |
1125 |
F |
0.40 |
| 167 |
1080 |
E |
1128 |
E |
0.40 |
| 168 |
1086 |
Y |
1134 |
E |
0.39 |
| 169 |
1050 |
P |
1054 |
P |
0.39 |
| 170 |
1113 |
L |
1137 |
I |
0.39 |
| 171 |
1088 |
E |
1136 |
E |
0.39 |
| 172 |
1093 |
F |
1133 |
K |
0.39 |
| 173 |
1121 |
L |
1133 |
K |
0.39 |
| 174 |
1090 |
V |
1106 |
E |
0.39 |
| 175 |
1077 |
G |
1125 |
F |
0.39 |
| 176 |
1100 |
E |
1112 |
Q |
0.39 |
| 177 |
1096 |
E |
1108 |
E |
0.39 |
| 178 |
1079 |
E |
1091 |
T |
0.38 |
| 179 |
1065 |
I |
1077 |
G |
0.38 |
| 180 |
1073 |
P |
1097 |
V |
0.38 |
| 181 |
1084 |
E |
1132 |
E |
0.38 |
| 182 |
1081 |
S |
1097 |
V |
0.38 |
| 183 |
1088 |
E |
1100 |
E |
0.38 |
| 184 |
1099 |
P |
1107 |
P |
0.38 |
| 185 |
1113 |
L |
1129 |
E |
0.38 |
| 186 |
1098 |
E |
1114 |
E |
0.37 |
| 187 |
1085 |
T |
1093 |
F |
0.37 |
| 188 |
1111 |
T |
1127 |
E |
0.37 |
| 189 |
1100 |
E |
1116 |
E |
0.37 |
| 190 |
1048 |
T |
1056 |
A |
0.37 |
| 191 |
1106 |
E |
1122 |
E |
0.37 |
| 192 |
1110 |
E |
1134 |
E |
0.37 |
| 193 |
1090 |
V |
1122 |
E |
0.37 |
| 194 |
1113 |
L |
1125 |
F |
0.37 |
| 195 |
1054 |
P |
1062 |
S |
0.37 |
| 196 |
1070 |
L |
1094 |
G |
0.37 |
| 197 |
1083 |
T |
1099 |
P |
0.37 |
| 198 |
1113 |
L |
1121 |
L |
0.37 |
| 199 |
1080 |
E |
1120 |
Q |
0.37 |
| 200 |
1130 |
E |
1134 |
E |
0.37 |
| 201 |
1071 |
I |
1119 |
T |
0.37 |
| 202 |
1080 |
E |
1096 |
E |
0.37 |
| 203 |
1087 |
T |
1119 |
T |
0.36 |
| 204 |
1084 |
E |
1096 |
E |
0.36 |
| 205 |
1109 |
F |
1121 |
L |
0.36 |
| 206 |
1137 |
I |
1141 |
Q |
0.36 |
| 207 |
1064 |
T |
1088 |
E |
0.36 |
| 208 |
1062 |
S |
1074 |
T |
0.36 |
| 209 |
1045 |
G |
1049 |
V |
0.36 |
| 210 |
1097 |
V |
1109 |
F |
0.36 |
| 211 |
1112 |
Q |
1136 |
E |
0.36 |
| 212 |
1108 |
E |
1124 |
E |
0.36 |
| 213 |
1080 |
E |
1116 |
E |
0.36 |
| 214 |
1086 |
Y |
1098 |
E |
0.35 |
| 215 |
1066 |
E |
1090 |
V |
0.35 |
| 216 |
1091 |
T |
1099 |
P |
0.35 |
| 217 |
1047 |
H |
1051 |
P |
0.35 |
| 218 |
1071 |
I |
1095 |
T |
0.35 |
| 219 |
1075 |
T |
1083 |
T |
0.35 |
| 220 |
1055 |
P |
1059 |
T |
0.34 |
| 221 |
1128 |
E |
1136 |
E |
0.34 |
| 222 |
1083 |
T |
1115 |
P |
0.34 |
| 223 |
1111 |
T |
1119 |
T |
0.34 |
| 224 |
1062 |
S |
1066 |
E |
0.34 |
| 225 |
1091 |
T |
1123 |
P |
0.34 |
| 226 |
1121 |
L |
1129 |
E |
0.34 |
| 227 |
1076 |
A |
1088 |
E |
0.34 |
| 228 |
1079 |
E |
1111 |
T |
0.34 |
| 229 |
1101 |
F |
1133 |
K |
0.34 |
| 230 |
1068 |
W |
1116 |
E |
0.34 |
| 231 |
1074 |
T |
1086 |
Y |
0.34 |
| 232 |
1114 |
E |
1126 |
E |
0.33 |
| 233 |
1133 |
K |
1141 |
Q |
0.33 |
| 234 |
1067 |
P |
1115 |
P |
0.33 |
| 235 |
1089 |
V |
1097 |
V |
0.33 |
| 236 |
1090 |
V |
1126 |
E |
0.33 |
| 237 |
1055 |
P |
1063 |
T |
0.33 |
| 238 |
1083 |
T |
1131 |
E |
0.33 |
| 239 |
1102 |
G |
1110 |
E |
0.33 |
| 240 |
1064 |
T |
1068 |
W |
0.33 |
| 241 |
1080 |
E |
1112 |
Q |
0.33 |
| 242 |
1115 |
P |
1127 |
E |
0.33 |
| 243 |
1082 |
E |
1114 |
E |
0.33 |
| 244 |
1062 |
S |
1086 |
Y |
0.33 |
| 245 |
1076 |
A |
1108 |
E |
0.33 |
| 246 |
1082 |
E |
1094 |
G |
0.33 |
| 247 |
1071 |
I |
1083 |
T |
0.32 |
| 248 |
1081 |
S |
1089 |
V |
0.32 |
| 249 |
1099 |
P |
1115 |
P |
0.32 |
| 250 |
1099 |
P |
1105 |
V |
0.32 |
| 251 |
1079 |
E |
1127 |
E |
0.32 |
| 252 |
1095 |
T |
1111 |
T |
0.32 |