Column: position in protein sequence. Row: amino acid substituted at position. x-labels show the wild-type SARS-CoV-2 amino acid followed by position (e.g. “A100”). Where SARS-CoV-2 is different than the SARS-CoV (2003) sequence, magenta x-labels include the SARS-CoV amino acid after the position (e.g. “A100K” for A in SARS-CoV-2 and K in SARS-CoV). Black “x”s show the SARS-CoV-2 amino acid at each position. Magenta “x”s show the SARS-CoV amino acid at each position, when different from SARS-CoV-2. Black lines show regions excluded due to low alignment coverage, these may be insertions largely unique to SARS-CoV-2. Magenta lines show deletions relative to SARS-CoV.
Mutation predictions using a simple model with only sitewise terms, not context specific.