Transmembrane Protein 3D Structures - Predicted by Evolutionary Couplings

2012 Comparison results of individual protein domains blindly predicted with experimentally KNOWN structures

Evolutionary couplings and predicted 3D folds for transmembrane proteins compared to known 3D structures.

Meff is the effective number of sequences in the alignment after weighting by the number of sequences with sequence identity above a similarity threshold.

The fold accuracy is measured by TM score - Template modeling scores (range 0.0 - 1.0). TM score is consided reasonable when > 0.5.

Cα-RMSD - root-mean-square deviation in Å (number of residues).

Uniprot ID PFAM TM Helices Length E-Val Meff Seq/len TM Score Cα-RMSD PDB Download link
ADIC_SALTY PF00324 12 394 20 24284 61.63 0.67 4.2 (300) 3ncyA download_results
ADRB2_HUMAN PF00001 7 296 20 35593 120.25 0.67 3.3 (201) 2rh1A download_results
ADT1_BOVIN PF00153 6 285 40 9828 34.48 0.48 3.8 (136) 1okcA download_results
AMTB_ECOLI PF00909 10 396 5 4407 11.13 0.67 3.9 (262) 1xqfA download_results
AQP4_HUMAN PF00230 6 215 10 6469 30.09 0.50 2.9 (100) 3gd8A download_results
BTUC_ECOLI PF01032 10 299 10 12926 43.23 0.67 3.2 (209) 1l7vA download_results
C3NQD8_VIBC PF01554 12 431 20 13864 32.17 0.62 4.6 (306) 3mktA download_results
C6E9S6_ECOBD PF00361 14 412 10 63730 154.68 0.63 4.2 (299) 3rkoN download_results
COX1_BOVIN PF00115 12 486 40 73822 151.90 0.66 3.7 (421) 1occA download_results
COX3_BOVIN PF00510 7 182 3 10705 58.82 0.69 2.8 (151) 1occC download_results
CYB_BOVIN PF00032/33 8 378 100 3727 9.86 0.66 3.9 (268) 1pp9C download_results
FIEF_ECOLI PF01545 6 197 5 9722 49.35 0.59 2.8 (119) 3h90A download_results
GLPG_ECOLI PF01694 6 169 5 5263 31.14 0.64 2.6 (126) 3b45A download_results
GLPT_ECOLI PF07690 12 402 30 24912 61.97 0.67 3.4 (363) 1pw4A download_results
METI_ECOLI PF00528 6 206 15 30400 147.57 0.46 3.5 (93) 3dhwA download_results
MIP_BOVIN PF00230 6 212 10 6468 22.59 0.55 3.1 (116) 1ymgA download_results
MSBA_SALTY PF00664 6 310 3 29034 93.66 0.57 3.3 (180) 3b60A download_results
O67854_AQUAE PF00209 12 463 3 4500 9.72 0.55 5.1 (274) 2a65A download_results
OPSD_BOVIN PF00001 7 274 20 35901 131.03 0.70 3.3 (214) 1hzxA download_results
Q87TN7_VIBPA (TRKH_VIBPA) PF02386 8 407 10 4097 10.01 0.59 4.0 (242) 3pjzA download_results
Q8EKT7_SHEON PF00854 12 447 10 12063 26.98 0.40 4.6 (180) 2xutA download_results
Q9K0A9_NEIMB PF01758 10 297 10 4244 14.29 0.44 3.6 (131) 3zuxA download_results
SGLT_VIBPA (SGLT_VIBPH) PF00474 14 487 5 9563 19.64 0.49 4.6 (214) 2xq2A download_results
TEHA_HAEIN PF03595 10 304 3 1860 6.12 0.51 4.1 (154) 3m71A download_results
URAA_ECOLI PF00860 14 393 3 14992 38.14 0.50 4.8 (194) 3qe7A download_results
Click here the current comparison results table.